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Cat. No.: HY-173159

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BMS-185354

BMS-185354 is a selective RARγ activator with an EC₅₀ value of 28 nM. BMS-185354 is promising for research of cancers.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 110952-22-2
Formule: C₂₆H₂₇NO₃
Masse moléculaire:401.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BMS-185354 Chemical Structure

CAS No.: 110952-22-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

BMS-185354 is a selective RARγ activator with an EC₅₀ value of 28 nM. BMS-185354 is promising for research of cancers^[1].

IC₅₀ & Target

RXRγ

28 nM (EC₅₀)

Voir tous les produits spécifiques à Isoform RAR/RXR :

Chemical Information

CAS No. 110952-22-2
Masse moléculaire 401.50
Formule C₂₆H₂₇NO₃
SMILES

O=C(C1=CC2=CC=C(/C(C3=CC=C4C(C(C)(CCC4(C)C)C)=C3)=N/O)C=C2C=C1)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ostrowski J, et al. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J Biol Chem. 1998 Feb 6;273(6):3490-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Cat. No.:
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BMS-185354

Voir tous les produits spécifiques à Isoform RAR/RXR

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BMS-185354 Related Classifications

HY-173159 Related Classifications

Bioz

Keywords

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