Catalponol
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 34168-56-4
- Formule: C15H18O2
- Masse moléculaire:230.30
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
In Vitro
In RAW 264.7 macrophage cells, Catalponol exhibits potent inhibitory effects with an IC50 value of 9.8 μM for inhibiting LPS-induced NO production[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 34168-56-4
-
Masse moléculaire 230.30
-
Formule C15H18O2
-
SMILES
O=C1C2=CC=CC=C2[C@@H](O)C[C@H]1C/C=C(C)/C
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. [Content Brief]
[2]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Catalponol Related Classifications
HY-N3550 Related Classifications
Powered by Bioz