CHIR 98024
Based on 1 Customer Validation
CHIR 98024 (Compound L) is a glycogen synthase kinase 3 (GSK3) inhibitor with an EC50 of 0.2566 μM.
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- Pureté: 99.20%
- CAS No.: 556813-39-9
- Formule: C20H17Cl2N9O2
- Masse moléculaire:486.31
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
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GSK-3 0.2566 μM (EC50) |
Chemical Information
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CAS No. 556813-39-9
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Appearance Solid
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Masse moléculaire 486.31
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Formule C20H17Cl2N9O2
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Color Light yellow to yellow
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SMILES
NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=CC=C(Cl)C=C4Cl)=N2)=CC=C1[N+]([O-])=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 125 mg/mL (257.04 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0563 mL | 10.2815 mL | 20.5630 mL | 51.4075 mL |
| 5 mM | 0.4113 mL | 2.0563 mL | 4.1126 mL | 10.2815 mL | |
| 10 mM | 0.2056 mL | 1.0282 mL | 2.0563 mL | 5.1408 mL | |
| 15 mM | 0.1371 mL | 0.6854 mL | 1.3709 mL | 3.4272 mL | |
| 20 mM | 0.1028 mL | 0.5141 mL | 1.0282 mL | 2.5704 mL | |
| 25 mM | 0.0823 mL | 0.4113 mL | 0.8225 mL | 2.0563 mL | |
| 30 mM | 0.0685 mL | 0.3427 mL | 0.6854 mL | 1.7136 mL | |
| 40 mM | 0.0514 mL | 0.2570 mL | 0.5141 mL | 1.2852 mL | |
| 50 mM | 0.0411 mL | 0.2056 mL | 0.4113 mL | 1.0282 mL | |
| 60 mM | 0.0343 mL | 0.1714 mL | 0.3427 mL | 0.8568 mL | |
| 80 mM | 0.0257 mL | 0.1285 mL | 0.2570 mL | 0.6426 mL | |
| 100 mM | 0.0206 mL | 0.1028 mL | 0.2056 mL | 0.5141 mL |