CJM061
CJM061 is a WEE1 kinase inhibitor with a target IC50 of 2.8 nM. CJM061 acts as a sensitizer and exhibits synergistic effects with Cisplatin (HY-17394) in medulloblastoma cells. CJM061 can be used for the research of medulloblastoma.
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- CAS No.: 1847445-87-7
- Formule: C28H32N8O4
- Masse moléculaire:544.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
CJM061 exhibits reduced single-agent cytotoxicity but shows synergistic activity with Cisplatin in medulloblastoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1847445-87-7
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Masse moléculaire 544.60
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Formule C28H32N8O4
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SMILES
O=C(N1CCN(CC1)C2=CC=C(NC3=NC=C4C(N(CC=C)N(C4=N3)C5=CC=CC(C(C)(C)O)=N5)=O)C=C2)OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)