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Cat. No.: HY-121293

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CP-944629

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 668990-94-1
Formule: C₁₉H₁₅F₃N₄O
Masse moléculaire:372.34

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CP-944629 Chemical Structure

CAS No.: 668990-94-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

CP-944629 (Compound 20) is an inhibitor of p38 alpha kinase with an IC₅₀ of 3.2. CP-944629 can be studied in research for chronic inflammation diseases^[1].

Voir tous les produits spécifiques à Isoform p38 MAPK :

Cellular Effect

Cell Line	Type	Value	Description	References
Monocyte	IC₅₀	8.3 nM Compound: 75	Inhibition of LPS-induced TNFalpha production in human monocytes Inhibition of LPS-induced TNFalpha production in human monocytes	[PMID: 16759861]

Chemical Information

CAS No. 668990-94-1
Masse moléculaire 372.34
Formule C₁₉H₁₅F₃N₄O
SMILES

FC1=C(C=C(C(C2=C(OC=N2)C3=CN4C(C=C3)=NN=C4C(C)(C)C)=C1)F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shashi Nayana, M. R., et al., (2008). CoMFA and docking studies on triazolopyridine oxazole derivatives as p38 MAP kinase inhibitors. European journal of medicinal chemistry, 43(6), 1261–1269. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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