Cyclamic acid calcium
Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine.
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- CAS No.: 139-06-0
- Formule: C6H13NO3S·1/2Ca
- Masse moléculaire:219.02
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 139-06-0
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Masse moléculaire 219.02
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Formule C6H13NO3S·1/2Ca
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SMILES
O=S(NC1CCCCC1)([O-])=O.[Ca+2].[1/2]
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Synonyms
Cyclohexylsulfamic acid calcium; Cyclamate calcium
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)