Dodecylamine
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Dodecylamine (Laurylamine) is a saturated aliphatic amine with cytotoxicity. Dodecylamine can act as a ligand for the extracellular recognition segment CD36149‑168 of the human CD36 receptor, with a human EC50 of 19 μM. After conjugation with BSA, Dodecylamine can increase hydrophobicity/amphiphilicity and promote self-assembly into cationic nanoparticles. Dodecylamine can be used in research related to CD36 receptor ligand recognition and nanoparticle synthesis.
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- Pureté : 98.77%
- CAS No.: 124-22-1
- Formule: C12H27N
- Masse moléculaire:185.36
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Stockage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
Activité biologique
Description
In Vitro
Dodecylamine binds human CD36149-168 saturably with an EC50 of 19 μM, behaving as a class B ligand; it shows extremely weak binding activity toward Scr‑FITC‑hCD36149‑168 (EC50 > 10000 μM), compared with an EC50 of 20 μM for the KK/DE‑FITC‑hCD36149‑168 peptide[2].
Dodecylamine can act as a cationic surfactant, bind to DNA, and slow down electron transfer reactions; it can be used to construct cobalt metal surfactant complexes[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 124-22-1
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Appearance <27°C Solid,>29°C Liquid
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Masse moléculaire 185.36
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Formule C12H27N
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Color Colorless to off-white
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SMILES
NCCCCCCCCCCCC
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Synonyms
Laurylamine
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvant et solubilité
In Vitro:
DMSO : 2 mg/mL (10.79 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (923 KB)
- English - EN (923 KB)
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- Italian - IT (923 KB)
- Korean - KR (923 KB)
- Portuguese - PT (923 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3949 mL | 26.9745 mL | 53.9491 mL | 134.8727 mL |
| 5 mM | 1.0790 mL | 5.3949 mL | 10.7898 mL | 26.9745 mL | |
| 10 mM | 0.5395 mL | 2.6975 mL | 5.3949 mL | 13.4873 mL |