DQn-1
DQn-1 is a potent antifolate with activity against Mycobacterium tuberculosis (Mtb) (MIC90=0.03 µM). DQn-1 directly inhibits DHFR enzyme activity, with IC50s of 8.7 and 7.6 nM for Mtb and human DHFR enzyme, respectively.
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- CAS No.: 57343-54-1
- Formule: C16H14ClN5O2
- Masse moléculaire:343.77
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
DQn-1 inhibits Mycobacterium tuberculosis, with MIC90s of 0.03 µM and 1 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57343-54-1
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Masse moléculaire 343.77
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Formule C16H14ClN5O2
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SMILES
O=C(C1=CC=C(NCC2=CC=C3N=C(N)N=C(C3=C2Cl)N)C=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)