ELQ-316
ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis.
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- CAS No.: 1354745-69-9
- Formule: C24H17F4NO4
- Masse moléculaire:459.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>10 μM
Compound: 18b, ELQ-316
|
Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate
Inhibition of human cytochrome bc1 complex derived from HEK293 cell mitochondria using 50 uM decylubiquinol as substrate
|
[PMID: 24720377] |
| HepG2 | IC50 |
>10 μM
Compound: 18b, ELQ-316
|
Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay
Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay
|
[PMID: 24720377] |
Chemical Information
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CAS No. 1354745-69-9
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Masse moléculaire 459.39
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Formule C24H17F4NO4
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SMILES
O=C1C2=CC(F)=C(C=C2NC(C)=C1C3=CC=C(OC4=CC=C(C=C4)OC(F)(F)F)C=C3)OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)