Glutaminase
Based on 1 Customer Validation
Glutaminase is a metabolic enzyme. Glutaminase catalyzes the hydrolysis of glutamine to glutamate. Glutaminase isoenzymes are encoded by Gls and Gls2 genes. Proteins GLS and GLS2 have different kinetic, immunologic, and molecular characteristics. Glutaminase can be used in the research of cancer.
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- CAS No.: 9001-47-2
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
EC Number
3.5.1.2
Specific Activity
50 - 200 U/mg protein
Unit Definition
One unit is defined as the amount of enzyme that will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37°C
Chemical Information
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CAS No. 9001-47-2
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[Glutaminase]
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Synonyms
GLS
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvant et solubilité
In Vitro:
H2O : 1 mg/mL (Need ultrasonic and warming)
Pureté et documentation
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Fiche technique (264 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010 Sep 14;18(3):207-19. [Content Brief]
[2]. Matés JM, et al. Glutaminase isoenzymes in the metabolic therapy of cancer. Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):158-164. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glutaminase Related Classifications
HY-P2760 Related Classifications
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