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Cat. No.: HY-N21952

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Heliotridine

Name: Heliotridine
Brand: MedChemExpress
SKU: HY-N21952
Availability: PreOrder

(Synonyms: (+)-Heliotridine)

Heliotridine ((+)-Heliotridine) is a monoesters-type necine base of pyrrolizidine alkaloid with genotoxic and antibacterial properties. Heliotridine can be isolated from the aerial parts of Heliotropium ellipticum, Heliotropium circinatum and other Heliotropium species (Boraginaceae). Heliotridine shows high tolerance in normal human hepatocytes (EC₅₀> 400 μM). Mediated by the organic cation transporter OCT1, Heliotridine exhibits in vitro growth inhibition and weak antibacterial activity against Drechslera tetramera. Heliotridine can be used in infection-related studies of specific pathogenic bacteria.

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CAS No.: 520-63-8
Formule: C₈H₁₃NO₂
Masse moléculaire:155.19

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Heliotridine Chemical Structure

CAS No.: 520-63-8

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

In Vitro

Heliotridine (2 mg; 0.1 g/mL) exhibits in vitro antimicrobial activity against Drechslera tetramera with a 7 mm zone of inhibition, and shows no measurable activity against all other tested bacteria and fungi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 520-63-8
Masse moléculaire 155.19
Formule C₈H₁₃NO₂
SMILES

OCC1=CCN2[C@@]1([H])[C@@H](O)CC2
Synonyms

(+)-Heliotridine
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. JAIN S C, et al. Antimicrobial activity of pyrrolizidine alkaloids from Heliotropium ellipticum[J]. Chemical and pharmaceutical bulletin, 1987, 35(8): 3487-3489.

[2]. Al-Suhail N, et al. Isolation of Pyrrolizidine Alkaloids from a Newly Recorded Heliotropium Species in Southern Basrah and Evaluation of its Anticancer Potential[J]. Eurasian Journal of Oncology, 2025, 13(3).

[3]. Haas M. Investigation of the hepatotoxic potency of selected genotoxic pyrrolizidine alkaloids and the significance of the DNA damage response[D]. Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau, 2025.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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