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Modotuximab

(Synonyms: DS 1024; Zatuximab)
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Modotuximab (DS 1024) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab binds non-overlapping epitopes on domain III of EGFR, a domain that is intact in EGFRvIII. Modotuximab has antitumor activity in vivo.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté : 99.08%
  • CAS No.: 1310460-86-6
  • Masse moléculaire:146.6 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Modotuximab
  • Experimental Validation Results for Modotuximab
  • Experimental Validation Results for Modotuximab
  • Modotuximab Chemical Structure
    Modotuximab Chemical Structure
CAS No.: 1310460-86-6
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Modotuximab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized HER2/CD340 Protein, Human can bind Modotuximab. The EC50 for this effect is 8.02 ng/mL.

  • 1/16

    Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Modotuximab (anti-ERBB1/EGFR/HER1) (HY-P99306). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Modotuximab Chemical Structure
    1/16
  • Modotuximab
  • Immobilized HER2/CD340 Protein, Human can bind Modotuximab. The EC50 for this effect is 8.02 ng/mL.
  • Flow Cytometry analysis of A431 cells labelling ERBB1/EGFR/HER1 (red) with Modotuximab (anti-ERBB1/EGFR/HER1) (HY-P99306). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.