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Cat. No.: HY-P99764

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Odesivimab

(Synonyms: REGN-3471)

1 Cited Publications

Avis client

Based on 1 publication(s) in Google Scholar

Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a K_D value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.64%
CAS No.: 2135632-30-1
Masse moléculaire:146.16 kDa

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Odesivimab Chemical Structure

CAS No.: 2135632-30-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Publications (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Virus

IC₅₀ & Target

Zaire Ebola virus

Voir tous les produits spécifiques à Isoform Filovirus :

In Vitro

Odesivimab (REGN-3471) neutralizes pseudovirus particles in vitro. Odesivimab with Atoltivimab and Maftivimab has an IC₅₀ value of 0.39 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Odesivimab with Atoltivimab and Maftivimab (REGN-3471; 50 mg/kg) has protective effect in the rhesus macaque model of Ebola virus infection^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

911829 [NCBI]

Accession

Q05320

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Human IgG1 kappa

Application

ELISA, FACS, Functional assay

Chemical Information

CAS No. 2135632-30-1
Appearance Liquid
Masse moléculaire 146.16 kDa
Color Colorless to light yellow
SMILES

[Odesivimab]
Synonyms

REGN-3471
Livraison

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Cell

Molecular characterization of Ebola virus glycoprotein V75A substitution in the 2018-2020 epidemic. [Abstract]

2026 Feb 5;189(3):818-831.e19. PMID: 41576953

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (257 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

Références

[1]. Markham A. REGN-EB3: First Approval. Drugs. 2021 Jan;81(1):175-178. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Odesivimab

1 Cited Publications

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Activité biologique
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Publications (1)
Pureté et documentation
Références

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Odesivimab

Antibody Inhibitor Library

Publications Citing Use of MedChemExpress (MCE) Odesivimab

Voir tous les produits spécifiques à Isoform Filovirus

Activité biologique

Chemical Information

Publications (1)

Pureté et documentation

Références

Calculators

Help & FAQs

Odesivimab

Cell-ATP Viability Detection Kit

Protein A Agarose

HOLO Human Interleukin-2 (IL-2) Detection Kit

Bradford Protein Assay Kit

PBS Buffer (1×)

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Antibody Inhibitor Library

Publications Citing Use of MedChemExpress (MCE) Odesivimab

Voir tous les produits spécifiques à Isoform Filovirus

Activité biologique

Chemical Information

Publications (1)

Pureté et documentation

Références

Calculators

Help & FAQs

Odesivimab Related Classifications

HY-P99764 Related Classifications