Phomalactone
Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L. Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons.
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- CAS No.: 28921-94-0
- Formule: C8H10O3
- Masse moléculaire:154.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| P388 | IC50 |
40.9 μM
Compound: 4
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
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[PMID: 17067166] |
Chemical Information
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CAS No. 28921-94-0
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Masse moléculaire 154.16
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Formule C8H10O3
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SMILES
O=C1C=C[C@H](O)[C@H](/C=C/C)O1
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Structure Classification
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Initial Source
Nigrospora sphaerica
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Filamentous Fungal Mold Culture and Sporulation
Filamentous fungal mold culture and sporulation assays grow hyphae under defined nutritional and environmental conditions until asexual spores, commonly conidia, are produced; the main readouts are colony growth, sporulation onset, conidial yield, conidial morphology, viability, and, when relevant, downstream infectivity or stress phenotype.
Pureté et documentation
Références
[1]. Kim JC, et al. Activity against plant pathogenic fungi of phomalactone isolated from Nigrospora sphaerica. Pest Manag Sci. 2001;57(6):554-559. [Content Brief]
[2]. Meepagala KM, et al. Phomalactone from a Phytopathogenic Fungus Infecting ZINNIA elegans (ASTERACEAE) Leaves. J Chem Ecol. 2015;41(7):602-612. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)