Piroctone
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research.
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- CAS No.: 50650-76-5
- Formule: C14H23NO2
- Masse moléculaire:237.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 50650-76-5
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Masse moléculaire 237.34
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Formule C14H23NO2
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SMILES
O=C1C=C(C)C=C(CC(CC(C)(C)C)C)N1O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Sigle HC, et al. In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans. Mycoses. 2006 May;49(3):159-68. [Content Brief]
[2]. Sidarovich V, et al. Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells. Mol Pharmacol. 2015;87(3):513-24. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Piroctone Related Classifications
HY-180521 Related Classifications
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