SC-50605
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..
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- CAS No.: 138828-39-4
- Formule: C30H35NO6S
- Masse moléculaire:537.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
LTB4[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
660 nM
Compound: 35
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Inhibitory activity against LTB4 production in HL60s.
Inhibitory activity against LTB4 production in HL60s.
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[PMID: 7699700] |
| HL-60 | IC50 |
928 nM
Compound: 35
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Inhibitory activity against PGE-2 production in HL60s.
Inhibitory activity against PGE-2 production in HL60s.
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[PMID: 7699700] |
Chemical Information
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CAS No. 138828-39-4
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Masse moléculaire 537.67
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Formule C30H35NO6S
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SMILES
O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SC-50605 Related Classifications
HY-117896 Related Classifications
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