TY-011
TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis (Apoptosis) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC50 value ranging from 0.11 to 4.49 μM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research.
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- CAS No.: 1389439-77-3
- Formule: C18H16ClN5
- Masse moléculaire:337.81
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
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Aurora A |
Aurora B |
Chemical Information
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CAS No. 1389439-77-3
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Masse moléculaire 337.81
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Formule C18H16ClN5
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SMILES
CC1=C(C(N2)=NN1)N=C(C3=CC=CC=C3Cl)C4=C2C=C(CC)N=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)