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Cat. No.: HY-119208

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VUF11211

VUF11211 is an allosteric inverse CXCR3 agonist with a K_d of 0.65 nM.

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CAS No.: 906556-51-2
Formule: C₂₆H₃₅Cl₂N₅O
Masse moléculaire:504.50

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

VUF11211 Chemical Structure

CAS No.: 906556-51-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

VUF11211 is an allosteric inverse CXCR3 agonist with a K_d of 0.65 nM^[1].

IC₅₀ & Target

Kd: 0.65 nM (CXCR3)^[1]

Voir tous les produits spécifiques à Isoform CXCR :

Cellular Effect

Cell Line	Type	Value	Description	References
BaF3	IC₅₀	0.3 nM Compound: 1	Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cells Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cells	[PMID: 22018463]

Chemical Information

CAS No. 906556-51-2
Masse moléculaire 504.50
Formule C₂₆H₃₅Cl₂N₅O
SMILES

ClC1=CC=C(C=C1)CN2CCC(CC2)N3[C@H](CN(CC3)C4=NC=C(C=C4Cl)C(NCC)=O)CC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Scholten DJ, et al. Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3. Mol Pharmacol. 2015 Apr;87(4):639-48. [Content Brief]

Calculators

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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VUF11211

Voir tous les produits spécifiques à Isoform CXCR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

VUF11211 Related Classifications

HY-119208 Related Classifications