YPLP
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active.
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- CAS No.: 2414391-44-7
- Formule: C25H36N4O6
- Masse moléculaire:488.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
YPLP (10-50 mg/kg, i.g. for 4 weeks) improves ATP levels and energy metabolism through phosphorylation of AMPK and promotion of AMPK proteins in fatigue ICR mice[1].
YPLP (10-50 mg/kg, i.g. for 4 weeks) regulates expressions of differential abundance proteins (DAPs), participates in the protein biosynthesis/degradation, muscle dynamics, and nuclear transport process to regulate muscle function in fatigue mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ICR mice[1]
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Dosage:10-50 mg/kg/d
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Administration:i.g. for 4 weeks
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Result:Increased levels of Nrf2, ATP, pAMPK and decreased levels of Keap1.
Chemical Information
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CAS No. 2414391-44-7
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Masse moléculaire 488.58
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Formule C25H36N4O6
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Sequence
Tyr-Pro-Leu-Pro
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Sequence Shortening
YPLP
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)