1086-80-2
1086-80-2
Chemical Structure
Lumichrome
- CAS No.: 1086-80-2
- Formula:C12H10N4O2
- Molecular Weight:242.24
IUPAC Name: 7,8-dimethylbenzo[g]pteridine-2,4(1H,3H)-dione
InChIKey: ZJTJUVIJVLLGSP-UHFFFAOYSA-N
SMILES: O=C(N1)NC2=NC3=CC(C)=C(C)C=C3N=C2C1=O
Biological Activity: Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lumichrome | 99.84% | Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway. | ||||||||||||||||||||
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Lumichrome (Standard) | 99.71% | Lumichrome (Standard) is the analytical standard of Lumichrome. This product is intended for research and analytical applications. Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway. | ||||||||||||||||||||
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Lumichrome-d8 | Lumichrome-d8 is the deuterium labeled Lumichrome (HY-115385). Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway. | |||||||||||||||||||||
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AG 1295 | 99.86% | AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR whereas not affects the autophosphorylation of the EGF receptor. | ||||||||||||||||||||
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Alloxazine | 99.46% | Alloxazine is a selective A2b antagonist. Alloxazine completely block 5’N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer. | ||||||||||||||||||||
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CK2-IN-10 | 99.70% | CK2-IN-10 (31), an allosteric CK2 inhibitor, can be used in the research of cancer. | ||||||||||||||||||||
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3,4,7,8-Tetramethyl-1,10-phenanthroline | 99.83% | 3,4,7,8-Tetramethyl-1,10-phenanthroline (TMPhen) is an organic molecule commonly used as a ligand or catalyst. It has a wide range of applications in different fields, such as organometallic chemical reactions, electrochemical detection, and organic optoelectronic devices. Due to its excellent performance in fluorescent probes, biosensors and photocatalytic reactions, it has been widely used in research in the fields of chemistry and life sciences. | ||||||||||||||||||||
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Neutral Red (IND) | 96.32% | Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. | ||||||||||||||||||||
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Acridine yellow G | Acridine yellow G is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. | |||||||||||||||||||||
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6,7-Diaminoquinoxaline-2,3-dione dihydrochloride | 6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes. | |||||||||||||||||||||
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Win-62005 | Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively. | |||||||||||||||||||||
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Pyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone | 99.90% | Pyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone (Pyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetrone) is a metal-organic framework (MOF). | ||||||||||||||||||||
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5-Deazaflavin | 95.0% | 5-deazaflavin is a flavin analogue with redox activity. 5-deazaflavin is a photocatalyst in biological redox systems. | ||||||||||||||||||||
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References
- [1]. Bergh VJ, et al. Influence of formulation on photoinactivation of bacteria by lumichrome. Pharmazie. 2015;70(9):574-580. [Content Brief]
- [2]. Chantarawong W, et al. Lumichrome Inhibits Human Lung Cancer Cell Growth and Induces Apoptosis via a p53-Dependent Mechanism. Nutr Cancer. 2019;71(8):1390-1402. [Content Brief]
