137-58-6
137-58-6
Chemical Structure
Lidocaine
Synonym(s): Lignocaine
- CAS No.: 137-58-6
- Formula:C14H22N2O
- Molecular Weight:234.34
IUPAC Name: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
InChIKey: NNJVILVZKWQKPM-UHFFFAOYSA-N
SMILES: O=C(NC1=C(C)C=CC=C1C)CN(CC)CC
Biological Activity: Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Lidocaine | 99.96% | Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia. | ||||||||||||||||||||
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Lidocaine (GMP) | Lidocaine (GMP) is Lidocaine (HY-B0185) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Lidocaine inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia. | |||||||||||||||||||||
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Lidocaine (Standard) | 99.97% | Lidocaine (Standard) is the analytical standard of Lidocaine. This product is intended for research and analytical applications. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia. | ||||||||||||||||||||
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Lidocaine-d6 | Lidocaine-d6 (Lignocaine-d6) is deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-B0185ALidocaine hydrochloride -
Similarity Score 0.96
HY-B0185BLidocaine hydrochloride hydrate -
Similarity Score 0.87
HY-Z6544N-(2,6-dimethylphenyl)-2-(ethyl(methyl)amino)acetamide hydrochloride -
Similarity Score 0.86
HY-117471Antiarrhythmic agent-3 -
Similarity Score 0.85
HY-Z6535RLidocaine impurity 12 (Standard) -
Similarity Score 0.84
HY-116738Trimecaine -
Similarity Score 0.84
HY-Z6540Lidocaine impurity 20 -
Similarity Score 0.82
HY-1149143-Hydroxylidocaine -
Similarity Score 0.82
HY-1534084-Hydroxylidocaine -
Explore the MedChemAI to find more analogs
References
- [1]. Cummins TR, et al. Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels. J Physiol. 2007 Jul 1;582(Pt 1):11. [Content Brief]
- [2]. Sui H, et al. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019 Mar 15;19(1):233. [Content Brief]
