1393-48-2
Chemical Structure
Thiostrepton
- CAS No.: 1393-48-2
- Formula:C72H85N19O18S5
- Molecular Weight:1664.89
InChIKey: NSFFHOGKXHRQEW-QKYCTTBPSA-N
SMILES: O=C([C@@H](NC(C(NC([C@@H](NC([C@](N[C@](C=C1)([H])[C@]2([H])O)([H])[C@@H](C)CC)=O)C)=O)=C)=O)C)N[C@](C3=NC(C(N[C@@](C(N/C(C4=N[C@]5([H])CS4)=C\C)=O)([H])[C@H](O)C)=O)=CS3)(CCC(C6=NC(C(NC(C(NC(C(N)=O)=C)=O)=C)=O)=CS6)=N7)[C@@]7([H])C8=CSC([C@@]([C@H](OC(C9=CC([C@@H](O)C)=C1C2=N9)=O)C)([H])NC(C%10=CSC([C@](NC5=O)([H])[C@](C)(O)[C@H](O)C)=N%10)=O)=N8
Biological Activity: Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thiostrepton | 99.80% | Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation. | ||||||||||||||||||||
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