157-06-2
Chemical Structure
D-Arginine
Synonym(s): H-D-Arg-OH
- CAS. Nr.: 157-06-2
- Formula:C6H14N4O2
- Molecular Weight:174.20
IUPAC Name: D-arginine
InChIKey: ODKSFYDXXFIFQN-SCSAIBSYSA-N
SMILES: N[C@H](CCCNC(N)=N)C(O)=O
Biological Activity: D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research[1][2][3][4][5][6][7][8].[1].
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D-Arginine | 98.0% | D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research.. | ||||||||||||||||||||
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D-Arginine (Standard) | ≥98% | D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research.. | ||||||||||||||||||||
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DL-Arginine | 98.0% | DL-Arginine is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells. | ||||||||||||||||||||
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L-Arginine | 99.89% | L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis. | ||||||||||||||||||||
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L-Arginine hydrochloride | 99.97% | L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis. | ||||||||||||||||||||
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L-Arginine-15N2 hydrochloride | 99.97% | L-Arginine-15N2 (hydrochloride) is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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L-Arginine-15N4 hydrochloride | 99.94% | L-Arginine-15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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L-Arginine-1-13C hydrochloride | 99.60% | L-Arginine-1-13C (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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L-Arginine-1,2-13C2 hydrochloride | 99.79% | L-Arginine-1,2-13C2 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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L-Arginine-13C6 hydrochloride | 99.92% | L-Arginine-13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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L-Arginine-13C6,15N4 hydrochloride | 99.85% | L-Arginine-13C6,15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. | ||||||||||||||||||||
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DL-Arginine hydrochloride | 98.0% | DL-Arginine ((±)-Arginine) hydrochloride is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells. | ||||||||||||||||||||
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References
- [1]. Eduardo Navarro , et al. Toxicological and Pharmacological Effects of D-arginine. Basic Clin Pharmacol Toxicol. 2005 Sep;97(3):149-54. [Content Brief]
- [2]. Chin-Dusting JP, et al. Effects of in vivo and in vitro L-arginine supplementation on healthy human vessels. J Cardiovasc Pharmacol. 1996 Jul;28(1):158-66. [Content Brief]
- [3]. Du C, et al. D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy. Biomaterials. 2021 Feb;269:120642. [Content Brief]
- [4]. Ma Y, et al. Direct cytosolic delivery of cargoes in vivo by a chimera consisting of D- and L-arginine residues. J Control Release. 2012 Sep 10;162(2):286-94. [Content Brief]
- [5]. Navarro E, et al. Toxicological and pharmacological effects of D-arginine. Basic Clin Pharmacol Toxicol. 2005 Sep;97(3):149-54. [Content Brief]
- [6]. Kim DR, et al. The effects of a comparatively higher dose of 1000 mg/kg/d of oral L- or D-arginine on the L-arginine metabolic pathways in male Sprague-Dawley rats. PLoS One. 2023 Aug 1;18(8):e0289476. [Content Brief]
- [7]. Kawabata A, et al. L-leucyl-L-arginine, naltrindole and D-arginine block antinociception elicited by L-arginine in mice with carrageenin-induced hyperalgesia. Br J Pharmacol. 1992 Dec;107(4):1096-101. [Content Brief]
- [8]. Zakaria ZA, et al. The effects of L-arginine, D-arginine, L-name and methylene blue on channa striatus-induced peripheral antinociception in mice. J Pharm Pharm Sci. 2005 Aug 3;8(2):199-206. [Content Brief]