178481-68-0

Hoechst 33342 analog Chemical Structure
178481-68-0

Chemical Structure

Hoechst 33342 analog

  • CAS No.: 178481-68-0
  • Formula:C32H37Cl2N7
  • Molecular Weight:590.59

IUPAC Name: N,N-bis(2-chloroethyl)-4-(3-(5-(4-methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)propyl)aniline

InChIKey: PZEAMYHHAKUANN-UHFFFAOYSA-N

SMILES: CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(CCCC6=CC=C(N(CCCl)CCCl)C=C6)N5)=C4)N3)=C2)CC1

Biological Activity: Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].

Cat. No. Product Name Purity Description Pricing
HY-15627 		Hoechst 33342 analog 96.73% Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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