2227110-54-3
2227110-54-3
Chemical Structure
3-IN-PP1
- CAS No.: 2227110-54-3
- Formula:C17H18N6
- Molecular Weight:306.37
IUPAC Name: 1-(tert-butyl)-3-(1H-indol-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: RBZLXANOQRQGTN-UHFFFAOYSA-N
SMILES: NC1=C2C(N(C(C)(C)C)N=C2C3=CNC4=C3C=CC=C4)=NC=N1
Biological Activity: 3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-IN-PP1 | 99.37% | 3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-139411-Naphthyl PP1 -
Similarity Score 0.76
HY-13941B1-Naphthyl PP1 hydrochloride -
Similarity Score 0.70
HY-151372Protein kinase D inhibitor 1 -
Similarity Score 0.68
HY-155587Hydroxy-PP -
Similarity Score 0.67
HY-13805PP2 -
Similarity Score 0.67
HY-13804PP1 -
Similarity Score 0.61
HY-128397CpCDPK1/TgCDPK1-IN-1 -
Similarity Score 0.61
HY-128399CpCDPK1/TgCDPK1-IN-3 -
Similarity Score 0.60
HY-118460ACJI-99C -
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