23779-99-9
23779-99-9
Chemical Structure
Floctafenine
- CAS No.: 23779-99-9
- Formula:C20H17F3N2O4
- Molecular Weight:406.36
IUPAC Name: 2,3-dihydroxypropyl 2-((8-(trifluoromethyl)quinolin-4-yl)amino)benzoate
InChIKey: APQPGQGAWABJLN-UHFFFAOYSA-N
SMILES: O=C(OCC(O)CO)C1=CC=CC=C1NC2=CC=NC3=C(C(F)(F)F)C=CC=C23
Biological Activity: Floctafenine, a nonsteroidal anti-inflammatory agent (NSAID), acts as an effective analgesic agent[1][2]. Floctafenine is an inhibitor of COX-1 and COX-2 activities in vitro,showing a slightly higher potency towards COX-I. Floctafenine is used for the research of short term pain research[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Floctafenine | 95.28% | Floctafenine, a nonsteroidal anti-inflammatory agent (NSAID), acts as an effective analgesic agent. Floctafenine is an inhibitor of COX-1 and COX-2 activities in vitro,showing a slightly higher potency towards COX-I. Floctafenine is used for the research of short term pain research. | ||||||||||||||||||||
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References
- [1]. P Giuseppe, et al. Floctafenine: a valid alternative in patients with adverse reactions to nonsteroidal anti-inflammatory drugs. Ann Allergy Asthma Immunol. 1997 Jan;78(1):74-8. [Content Brief]
- [2]. Gehan Hegazy Hegazy, et al. Synthesis of some floctafenine derivatives of expected anti-inflammatory/analgesic activity. Arch Pharm (Weinheim). 2005 Aug;338(8):378-84. [Content Brief]
- [3]. R Maenthaisong, et al. Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects.Int J Immunopathol Pharmacol. Apr-Jun 2013;26(2):403-17. [Content Brief]
Keywords
