244240-24-2
244240-24-2
Chemical Structure
(Z)-LFM-A13
- CAS No.: 244240-24-2
- Formula:C11H8Br2N2O2
- Molecular Weight:360.01
IUPAC Name: (Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
InChIKey: UVSVTDVJQAJIFG-VURMDHGXSA-N
SMILES: BrC1=C(NC(/C(C#N)=C(C)\O)=O)C=C(Br)C=C1
Biological Activity: LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM; LFM-A13 shows no effects on JAK1 and JAK3, Src family kinase HCK, EGFR and IRK.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Z)-LFM-A13 | 99.80% | LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM; LFM-A13 shows no effects on JAK1 and JAK3, Src family kinase HCK, EGFR and IRK. | ||||||||||||||||||||
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