263261-64-9
263261-64-9
Chemical Structure
Bisphenol A-13C2
- CAS No.: 263261-64-9
- Formula:C1313C2H16O2
- Molecular Weight:230.27
InChIKey: IISBACLAFKSPIT-ZDOIIHCHSA-N
SMILES: [13CH3]C(C1=CC=C(O)C=C1)(C2=CC=C(O)C=C2)[13CH3]
Biological Activity: Bisphenol A-13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisphenol A-13C2 | Bisphenol A-13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | |||||||||||||||||||||
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Bisphenol A (Standard) | 99.79% | Bisphenol A (Standard) is the analytical standard of Bisphenol A. This product is intended for research and analytical applications. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d16 | 99.95% | Bisphenol A-d16 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d4-1 | 99.53% | Bisphenol A-d4-1 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d6 | 99.04% | Bisphenol A-d6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d14 | 99.71% | Bisphenol A-d14 is a deuterium labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-13C12 | 96.38% | Bisphenol A-13C12 is the 13C-labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d8 | 99.26% | Bisphenol A-d8 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Bisphenol A-d4 | Bisphenol A-d4 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | |||||||||||||||||||||
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Bisphenol A | 99.91% | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders. | ||||||||||||||||||||
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Dimethyl-bisphenol A | 99.78% | Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression. | ||||||||||||||||||||
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2,2-Bis(p-hydroxyphenyl)-1,1,1-trichloroethane-d8 | 2,2-Bis(p-hydroxyphenyl)-1,1,1-trichloroethane-d8 is the deuterated-labeled HPTE (HY-W490804). HPTE is the active in vivo metabolite of Methoxychlor (HY-B1873), and acts as an inhibitor of 3β‑HSD and 17β‑HSD3. HPTE binds to the substrate-binding pocket of 3β‑HSD in a non-competitive manner, but competitively occupies the coenzyme NAD+-binding site, thereby inhibiting the conversion of pregnenolone to progesterone. HPTE binds to the androstenedione-binding pocket (the substrate pocket) of 17β‑HSD3 in a non-competitive manner, and competitively occupies the coenzyme NADPH-binding site, thus blocking the conversion of androstenedione to testosterone. HPTE interferes with androgen biosynthesis in Leydig cells by inhibiting the activities of these two key steroidogenic enzymes. HPTE can be used in studies related to androgen biosynthesis. | |||||||||||||||||||||
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Bisphenol A monosulfate-d6 sodium | Bisphenol A monosulfate-d6 (sodium) is the deuterium labeled Bisphenol A monosulfate sodium. | |||||||||||||||||||||
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2,2'-Dichloro bisphenol A-d12 | 2,2'-Dichloro bisphenol A-d12 is the deuterium labeled 2,2'-Dichloro bisphenol A. | |||||||||||||||||||||
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2,6-Dichloro bisphenol A-d12 | 2,6-Dichloro bisphenol A-d12 is the deuterium labeled 2,6-Dichloro bisphenol A. | |||||||||||||||||||||
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Benzil-d10 | Benzil-d10 is the deuterium labeled Benzil. | |||||||||||||||||||||
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(Rac)-Hexestrol-d4 | (Rac)-Hexestrol-d4 is the deuterium labeled (Rac)-Hexestrol. | |||||||||||||||||||||
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(Rac)-Hexestrol-d6 | (Rac)-Hexestrol-d6 is the deuterium labeled (Rac)-Hexestrol. | |||||||||||||||||||||
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Hexestrol-d4 | 97.49% | Hexestrol-d4 is the deuterium labeled Hexestrol (HY-B1662). Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle. | ||||||||||||||||||||
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p,p'-DDD-d8 | p,p'-DDD-d8 is the deuterium labeled p,p'-DDD. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats. | |||||||||||||||||||||
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Bis(4-Methoxyphenyl)methanone-d8 | Bis(4-Methoxyphenyl)methanone-d8 is the deuterium labeled Bis(4-Methoxyphenyl)methanone. | |||||||||||||||||||||
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Bisphenol B | 99.34% | Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties. | ||||||||||||||||||||
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Bisphenol B (Standard) | ≥98% | Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties. | ||||||||||||||||||||
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4,4'-Dihydroxybenzophenone | 99.33% | 4,4'-Dihydroxybenzophenone is a type of phenolic ultraviolet absorber and a drug intermediate for synthesis of various anticancer active compounds (such as Sivifene (HY-14801)). 4,4'-Dihydroxybenzophenone binds to the active site of trypsin with binding constants (KA = 7.59 x 105 L/moL) and leads to abnormal structure of trypsin, suggesting that long-term intake may affect the digestive function of the human body. 4,4’-dihydroxybenzophenone has a relatively low toxicity to Chlorella vulgaris and a moderate toxicity to Daphnia magna. | ||||||||||||||||||||
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4-Cumylphenol | 99.70% | 4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes. | ||||||||||||||||||||
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Bisphenol E | 99.90% | Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent. | ||||||||||||||||||||
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3-Chlorobisphenol A | 95.19% | 3-Chlorobisphenol A, a chlorinated derivatives of bisphenol A, is an endocrine-disrupting compound. It binds to estrogen receptors, causing disorders in hormone signaling pathways. Bisphenol A is an industrial chemical used in the production of polycarbonate plastics and epoxy resin. | ||||||||||||||||||||
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Bisphenol B-d8 | 98.89% | Bisphenol B-d8 is the deuterium labeled Bisphenol B (HY-W013935). Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC). Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models. | ||||||||||||||||||||
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Bisphenol AF-13C12 | Bisphenol AF-13C12 is an isotopic label of Bisphenol AF. Bisphenol AF is used in polycarbonate plastic and epoxy resin manufacturing. Bisphenol AF can significantly increase intracellular ROS levels. | |||||||||||||||||||||
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Bisphenol P-13C4 | Bisphenol P-13C4 is 13C labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Huang M, et al. Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells. Chemosphere. 2020 Apr 9;253:126707. [Content Brief]
- [3]. Rubin BS, et al. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):27-34. [Content Brief]
