Bisphenol A-13C12
Based on 1 Customer Validation
Bisphenol A-13C12 is the 13C-labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.
For research use only. We do not sell to patients.
- Purity: 96.38%
- CAS No.: 263261-65-0
- Formula: C313C12H16O2
- Molecular Weight:240.20
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 263261-65-0
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Unlabeled Cas 80-05-7
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Appearance Solid
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Molecular Weight 240.20
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Formula C313C12H16O2
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Color White to light yellow
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SMILES
CC([13C]1=[13CH][13CH]=[13C]([13CH]=[13CH]1)O)([13C]2=[13CH][13CH]=[13C]([13CH]=[13CH]2)O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (416.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (863 KB)
- English - EN (863 KB)
- Français - FR (863 KB)
- Deutsch - DE (863 KB)
- Norwegian - NO (863 KB)
- Español - ES (863 KB)
- Swedish - SV (863 KB)
- Italian - IT (863 KB)
- Portuguese - PT (863 KB)
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Handling Instructions (2659 KB)
References
[1]. Huang M, et al. Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells. Chemosphere. 2020 Apr 9;253:126707. [Content Brief]
[2]. Rubin BS, et al. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):27-34. [Content Brief]
[3]. Xu J, et al. Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells. Biochem Biophys Res Commun. 2002 Mar 29;292(2):456-62. [Content Brief]
[4]. Qu W, et al. Bisphenol A suppresses proliferation and induces apoptosis in colonic epithelial cells through mitochondrial and MAPK/AKT pathways. Life Sci. 2018 Sep 1;208:167-174. [Content Brief]
[5]. Hwang JK, et al. Bisphenol A reduces differentiation and stimulates apoptosis of osteoclasts and osteoblasts. Life Sci. 2013 Sep 17;93(9-11):367-72. [Content Brief]
[6]. Michałowicz J, et al. Bisphenol A and its analogs induce morphological and biochemical alterations in human peripheral blood mononuclear cells (in vitro study). Toxicol In Vitro. 2015 Oct;29(7):1464-72. [Content Brief]
[7]. Lin Y, et al. Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells. Cell Death Dis. 2013 Jan 17;4(1):e460. [Content Brief]
[8]. Takahashi O, et al. Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and mice. Food Chem Toxicol. 2003 Jul;41(7):1035-44. [Content Brief]
[9]. Morrissey RE, et al. The developmental toxicity of bisphenol A in rats and mice. Fundam Appl Toxicol. 1987 May;8(4):571-82. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1632 mL | 20.8160 mL | 41.6320 mL | 104.0799 mL |
| 5 mM | 0.8326 mL | 4.1632 mL | 8.3264 mL | 20.8160 mL | |
| 10 mM | 0.4163 mL | 2.0816 mL | 4.1632 mL | 10.4080 mL | |
| 15 mM | 0.2775 mL | 1.3877 mL | 2.7755 mL | 6.9387 mL | |
| 20 mM | 0.2082 mL | 1.0408 mL | 2.0816 mL | 5.2040 mL | |
| 25 mM | 0.1665 mL | 0.8326 mL | 1.6653 mL | 4.1632 mL | |
| 30 mM | 0.1388 mL | 0.6939 mL | 1.3877 mL | 3.4693 mL | |
| 40 mM | 0.1041 mL | 0.5204 mL | 1.0408 mL | 2.6020 mL | |
| 50 mM | 0.0833 mL | 0.4163 mL | 0.8326 mL | 2.0816 mL | |
| 60 mM | 0.0694 mL | 0.3469 mL | 0.6939 mL | 1.7347 mL | |
| 80 mM | 0.0520 mL | 0.2602 mL | 0.5204 mL | 1.3010 mL | |
| 100 mM | 0.0416 mL | 0.2082 mL | 0.4163 mL | 1.0408 mL |
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