2756809-34-2
2756809-34-2
Chemical Structure
HDAC-IN-30
- CAS No.: 2756809-34-2
- Formula:C22H23N5O3
- Molecular Weight:405.45
IUPAC Name: N-hydroxy-7-((8-oxo-8H-phthalazino[1,2-b]quinazolin-5-yl)amino)heptanamide
InChIKey: FRODMJXAOPBPTI-UHFFFAOYSA-N
SMILES: O=C(NO)CCCCCCNC(C1=C2C=CC=C1)=NN3C2=NC4=C(C=CC=C4)C3=O
Biological Activity: HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 (IC50=13.4 nM),HDAC2 (IC50=28.0 nM), HDAC3 (IC50=9.18 nM), HDAC6 (IC50=42.7 nM), HDAC8 (IC50=131 nM). HDAC-IN-30 exhibits potent antitumor efficacy[1].
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HDAC-IN-30 | HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 (IC50=13.4 nM),HDAC2 (IC50=28.0 nM), HDAC3 (IC50=9.18 nM), HDAC6 (IC50=42.7 nM), HDAC8 (IC50=131 nM). HDAC-IN-30 exhibits potent antitumor efficacy. | |||||||||||||||||||||
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