393781-65-2

cRGDfK-thioacetyl ester Chemical Structure
393781-65-2

Chemical Structure

cRGDfK-thioacetyl ester

  • CAS No.: 393781-65-2
  • Formula:C31H45N9O9S
  • Molecular Weight:719.81

InChIKey: FXPPTLMPDATYHN-GPJHCHHRSA-N

SMILES: O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CSC(C)=O)=O)[C@H]1CC2=CC=CC=C2

Biological Activity: cRGDfK-thioacetyl ester is a selective αvβ3 integrin-binding peptide that mediates cellular uptake through integrins overexpressed on tumor cells. cRGDfK-thioacetyl ester is conjugated to maleimide-functionalized PLGA nanoparticles, which enhances nanoparticle uptake and improves accumulation and retention. cRGDfK-thioacetyl ester can be used in research related to tumor-targeted nanodelivery and cancer-targeted imaging[1].

Cat. No. Product Name Purity Description Pricing
HY-P5287 		cRGDfK-thioacetyl ester 98.20% cRGDfK-thioacetyl ester is a selective αvβ3 integrin-binding peptide that mediates cellular uptake through integrins overexpressed on tumor cells. cRGDfK-thioacetyl ester is conjugated to maleimide-functionalized PLGA nanoparticles, which enhances nanoparticle uptake and improves accumulation and retention. cRGDfK-thioacetyl ester can be used in research related to tumor-targeted nanodelivery and cancer-targeted imaging.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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