40172-65-4
40172-65-4
Chemical Structure
SKA-31
- CAS No.: 40172-65-4
- Formula:C11H8N2S
- Molecular Weight:200.27
IUPAC Name: naphtho[1,2-d]thiazol-2-amine
InChIKey: FECQXVPRUCCUIL-UHFFFAOYSA-N
SMILES: NC1=NC2=C3C=CC=CC3=CC=C2S1
Biological Activity: SKA-31 is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SKA-31 | 99.66% | SKA-31 is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. | ||||||||||||||||||||
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SKA-31 (Standard) | ≥98% | SKA-31 (Standard) is the analytical standard of SKA-31. This product is intended for research and analytical applications. SKA-31 is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-100418SKA-111 -
Similarity Score 0.72
HY-W017424R2-Aminobenzothiazole (Standard) -
Similarity Score 0.69
![Benzo[h]quinoline Chemical Structure](//file.medchemexpress.com/product_pic/hy-w004769.gif)
HY-W004769Benzo[h]quinoline -
Similarity Score 0.66
HY-114652AalphaC -
Similarity Score 0.66
HY-W700491AalphaC-15N3 -
Similarity Score 0.66
HY-W0075242-Aminoquinoline -
Similarity Score 0.66
HY-1211731-Aminoacridine -
Similarity Score 0.65
HY-W403607CBIQ -
Similarity Score 0.65
HY-1351896-Aminophenanthridine -
Explore the MedChemAI to find more analogs
![Benzo[h]quinoline Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w004769.gif)
