40957-83-3
40957-83-3
Chemical Structure
Glycitein
Synonym(s): Glycetein
- CAS No.: 40957-83-3
- Formula:C16H12O5
- Molecular Weight:284.26
IUPAC Name: 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
InChIKey: DXYUAIFZCFRPTH-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=C(O)C=C1)=CO2)C3=C2C=C(O)C(OC)=C3
Biological Activity: Glycitein is a soy isoflavone used to study apoptosis and antioxidant[1][2][3].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Glycitein | 99.72% | Glycitein is a soy isoflavone used to study apoptosis and antioxidant. | ||||||||||||||||||||
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Glycitein (Standard) | ≥98% | Glycitein (Standard) is the analytical standard of Glycitein. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Texasin | 99.14% | Texasin is a natural product that can be isolated from Baptisia australis. | ||||||||||||||||||||
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Afromosin | 99.68% | Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects. | ||||||||||||||||||||
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Calycosin | 99.96% | Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer. | ||||||||||||||||||||
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3'-Methoxydaidzein | 99.67% | 3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. | ||||||||||||||||||||
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Prunetin (Standard) | ≥98% | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. | ||||||||||||||||||||
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Desmethylglycitein | 99.99% | Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes. | ||||||||||||||||||||
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Isoformononetin | 99.47% | Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions. | ||||||||||||||||||||
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5-O-Methylgenistein | 99.03% | 5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast. | ||||||||||||||||||||
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Alfalone | Alfalone (compound 9ia) is an antimitotic agent. Alfalone causes cleavage arrest and initiates the formation of tuberculate eggs. | |||||||||||||||||||||
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Glycitein-7-O-methyl ether | Glycitein-7-O-methyl ether (6-Methoxyisoformononetin) is an isoflavone antioxidant with a IC50 of 730.53 µg/mL. Glycitein-7-O-methyl ether exhibits weak free radical scavenging activity and shows no antibacterial activity against tested bacteria and fungi. Glycitein-7-O-methyl ether can be used in antioxidant-related research. | |||||||||||||||||||||
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References
- [1]. Song TT, et al. Estrogenic activity of glycitein, a soy isoflavone. J Agric Food Chem. 1999 Apr;47(4):1607-10. [Content Brief]
- [2]. Yoshida H, et al. Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem. 2001 May;65(5):1211-3. [Content Brief]
- [3]. Pan W, et al. Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats. J Nutr. 2001 Apr;131(4):1154-8. [Content Brief]
