568-80-9
568-80-9
Chemical Structure
Galloflavin
- CAS No.: 568-80-9
- Formula:C12H6O8
- Molecular Weight:278.17
IUPAC Name: 3,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,6-dione
InChIKey: VYKVZHXHVUVABA-UHFFFAOYSA-N
SMILES: O=C(OC(C=C1O)=C2OC1=O)C3=C2C(O)=C(O)C(O)=C3
Biological Activity: Galloflavin is a potent lactate dehydrogenase (LDH) inhibitor. The calculated Kis for pyruvate are 5.46 μM (LDH-A) and 15.06 μM (LDH-B). Galloflavin hinders the proliferation of cancer cells by blocking glycolysis and ATP production[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Galloflavin | 99.36% | Galloflavin is a potent lactate dehydrogenase (LDH) inhibitor. The calculated Kis for pyruvate are 5.46 μM (LDH-A) and 15.06 μM (LDH-B). Galloflavin hinders the proliferation of cancer cells by blocking glycolysis and ATP production. | ||||||||||||||||||||
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References
- [1]. Manerba M, Vettraino M, Fiume L, et al. Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. ChemMedChem. 2012;7(2):311-317. [Content Brief]
- [2]. Farabegoli F, et al. Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways. Eur J Pharm Sci. 2012;47(4):729-738. [Content Brief]
Keywords
