65147-22-0
65147-22-0
Chemical Structure
N-CBZ-Phe-Arg-AMC
Synonym(s): Z-FR-AMC
- CAS No.: 65147-22-0
- Formula:C33H36N6O6
- Molecular Weight:612.68
IUPAC Name: benzyl ((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
InChIKey: ZZGDDBWFXDMARY-SVBPBHIXSA-N
SMILES: CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)=O)C=C1O4)=CC4=O
Biological Activity: N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
N-CBZ-Phe-Arg-AMC | 99.40% | N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Volle B, et al. Myoglobin inhibition of most protease activities measured with fluorescent substrates is an artifact!. Meat Sci. 1999;52(1):81-87. [Content Brief]
- [2]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014;30(2-3):246-253. [Content Brief]
