66-23-9
66-23-9
Chemical Structure
Acetylcholine bromide
Synonym(s): ACh bromide
- CAS No.: 66-23-9
- Formula:C7H16BrNO2
- Molecular Weight:226.11
IUPAC Name: 2-acetoxy-N,N,N-trimethylethan-1-aminium bromide
InChIKey: ZEHGKSPCAMLJDC-UHFFFAOYSA-M
SMILES: O=C(OCC[N+](C)(C)C)C.[Br-]
Biological Activity: Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro[5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acetylcholine bromide | 99.02% | Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d4 bromide | 98.0% | Acetylcholine-d4 (ACh-d4) bromide is the deuterated-labeled Acetylcholine bromide (HY-B0282A). Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d9 bromide | 98.47% | Acetylcholine-d9 (ACh-d9) bromide is the deuterated-labeled Acetylcholine bromide (HY-B0282A). Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d13 bromide | 98.55% | Acetylcholine-d13 (ACh-d13) bromide is the deuterated-labeled Acetylcholine bromide (HY-B0282A). Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d16 bromide | 98.0% | Acetylcholine-d16 (ACh-d16) bromide is the deuterated-labeled Acetylcholine bromide (HY-B0282A). Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine iodide | 98.59% | Acetylcholine (ACh) iodide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine iodide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine iodide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine iodide (Standard) | ≥98% | Acetylcholine iodide (Standard) (ACh iodide (Standard)) is the analytical standard of Acetylcholine iodide (HY-101086). This product is intended for research and analytical applications. Acetylcholine (ACh) iodide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine iodide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine iodide inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetyl-L-carnitine-d9 | Acetyl-L-carnitine-d9 (O-Acetyl-L-carnitine-d9) is deuterium labeled Acetyl-L-carnitine. Acetyl-L-carnitine (O-Acetyl-L-carnitine) is a compound involved in human metabolic research. It has relevant applications in predicting metabolite biomarker changes using the Recon 2 metabolic reconstruction model and integrating and analyzing multiple data types, but its specific activity mechanism is not described in detail based on the existing information. | |||||||||||||||||||||
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Actinine-d9 chloride | 98.01% | Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat. | ||||||||||||||||||||
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delta-Valerobetaine-d9 chloride | 98.0% | delta-Valerobetaine-d9 chloride is the deuterium labeled delta-Valerobetaine (HY-114202). delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO). | ||||||||||||||||||||
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Acetylcholine perchlorate | Acetylcholine perchlorate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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AETA | AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems. | |||||||||||||||||||||
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Ethyl (S)-2-hydroxy-3-methylbutyrate-d5 | Ethyl (S)-2-hydroxy-3-methylbutyrate-d5 is deuterated labeled Ethyl (S)-2-hydroxy-3-methylbutyrate. | |||||||||||||||||||||
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NH2-C2-NH-Boc-d4 | NH2-C2-NH-Boc-d4 is the deuterium labeled NH2-C2-NH-Boc. NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Methacholine bromide | Methacholine (Acetyl-β-methylcholine) bromide is a potent muscarinic-3 (M3) agonist. Methacholine bromide acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine bromide shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine bromide can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates. | |||||||||||||||||||||
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Acetylcholine chloride | 99.91% | Acetylcholine (ACh) chloride, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d4 chloride | 99.97% | Acetylcholine-d4 (ACh-d4) chloride is the deuterated-labeled Acetylcholine chloride (HY-B0282). Acetylcholine (ACh) chloride, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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Acetylcholine-d9 chloride | 99.96% | Acetylcholine-d9 (ACh-d9) chloride is the deuterated-labeled Acetylcholine (chloride) (HY-B0282). Acetylcholine (ACh) chloride, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro. | ||||||||||||||||||||
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L-Carnitine-d9 | 99.0% | L-Carnitine-d9 is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism. | ||||||||||||||||||||
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Choline-d4 chloride | 99.90% | Choline-d4 chloride is the d4-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma. | ||||||||||||||||||||
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Choline-d9 chloride | 99.98% | Choline-d9 chloride is the d9-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma. | ||||||||||||||||||||
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Chlorocholine-d9 chloride | Chlorocholine-d9 (chloride) is the deuterium labeled Chlorocholine chloride. Chlorocholine chloride is an effective plant growth regulator. Chlorocholine chloride can inhibit gibberellin (GA) biosynthesis. Chlorocholine chloride can be used for the research of the mechanisms and effects of GA on plant cell growth and differentiation. | |||||||||||||||||||||
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Betaine-d9 chloride | 99.66% | Betaine-d9 (chloride) is the deuterium labeled Betaine chloride. | ||||||||||||||||||||
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Butyrylcholine iodide | 99.83% | Butyrylcholine Iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Butyrylcholine chloride | 98.0% | Butyrylcholine (chloride) is a biochemical assay reagent. | ||||||||||||||||||||
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[2-(Methacryloyloxy)ethyl]trimethylammonium chloride | [2-(Methacryloyloxy)ethyl]trimethylammonium chloride is a biochemical assay reagent. | |||||||||||||||||||||
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Choline-1,1,2,2-d4 bromide | Choline-1,1,2,2-d4 (bromide) is the deuterium labeled Choline-1,1,2,2 bromide. | |||||||||||||||||||||
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Choline-d9 bromide | Choline-d9 (bromide) is the deuterium labeled Choline bromide. | |||||||||||||||||||||
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Cholamine-d9 | Cholamine-d9 is the deuterium labeled Cholamine. | |||||||||||||||||||||
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Choline acetate | 99.90% | Choline acetate is a choline-based ionic liquid. Choline acetate can promote lipase activity. Choline acetate can also be used as a plasticizer or ionic liquid component to improve carrier structure and release properties, thereby enhancing the performance of biomaterials. | ||||||||||||||||||||
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References
- [1]. Prashant Tiwari, et al. Basic and modern concepts on cholinergic receptor: A review. Asian Pac J Trop Dis. 2013 Oct;3(5): 413-420.
- [2]. A Young, et al. Diarrhoea of famine and malnutrition--investigations using a rat model. 2--Ileal hypersecretion induced by starvation. Gut. 1990 Feb;31(2):162-9. [Content Brief]
- [5]. Zhaolin Chen, et al. Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride. Protein Pept Lett. 2017;24(4):353-357. [Content Brief]
