83-72-7
83-72-7
Chemical Structure
Lawsone
- CAS No.: 83-72-7
- Formula:C10H6O3
- Molecular Weight:174.16
IUPAC Name: 2-hydroxynaphthalene-1,4-dione
InChIKey: CSFWPUWCSPOLJW-UHFFFAOYSA-N
SMILES: O=C1C(O)=CC(C2=C1C=CC=C2)=O
Biological Activity: Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research[1][2][3][4][5].
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Lawsone | 99.54% | Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research. | ||||||||||||||||||||
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Lawsone (Standard) | ≥98% | Lawsone is an orally active naphthoquinone dye that can be isolated from the leaves of Lawsonia inermis. Lawsone can induce apoptosis. Lawsone has antibacterial, antitumor and antioxidant activities. Lawsone can be used in anti-tumor drug research. | ||||||||||||||||||||
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Lawsone-d4 | Lawsone-d4 is the deuterium labeled Lawsone. Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity. | |||||||||||||||||||||
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References
- [1]. Tripathi RD, et al. A fungitoxic principle from the leaves of lawsonia inermis lam. Experientia. 1978 Jan 15;34(1):51-2. [Content Brief]
- [2]. Munday R, et al. Haemolytic activity and nephrotoxicity of 2-hydroxy-1,4-naphthoquinone in rats. J Appl Toxicol. 1991 Apr;11(2):85-90. [Content Brief]
- [3]. Sauriasari R, et al. Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli. Toxicology. 2007 Jun 3;235(1-2):103-11. [Content Brief]
- [4]. Wang SB, et al. Lawsone suppresses azoxymethane mediated colon cancer in rats and reduces proliferation of DLD-1 cells via NF-κB pathway. Biomed Pharmacother. 2017 May;89:152-161. [Content Brief]
- [5]. Li P, et al. Lawsone inhibits cell growth and improves the efficacy of cisplatin in SKOV-3 ovarian cancer cell lines. African Journal of Traditional, Complementary and Alternative Medicines, 2017, 14(5): 8-17.
Keywords
