941575-71-9
941575-71-9
Chemical Structure
BIP-135
- CAS No.: 941575-71-9
- Formula:C21H13BrN2O3
- Molecular Weight:421.24
IUPAC Name: 3-(benzofuran-3-yl)-4-(5-bromo-1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
InChIKey: QKQJCKAXFJBYKJ-UHFFFAOYSA-N
SMILES: O=C(C(C1=COC2=CC=CC=C12)=C3C4=CN(C)C5=C4C=C(Br)C=C5)NC3=O
Biological Activity: BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect[1].
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BIP-135 | 99.38% | BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect. | ||||||||||||||||||||
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BIP-135 (Standard) | ≥98% | BIP-135 (Standard) is the analytical standard of BIP-135 (HY-111055). This product is intended for research and analytical applications. BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect. | ||||||||||||||||||||
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