CatD-IN-1
Based on 1 Customer Validation
CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM. CatD-IN-1 holds potential for research in the field of osteoarthritis .
For research use only. We do not sell to patients.
- Purity: 99.27%
- CAS No.: 1628521-28-7
- Formula: C18H18Cl2N4O5
- Molecular Weight:441.27
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Cathepsin Isoforms
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Biological Activity
Chemical Information
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CAS No. 1628521-28-7
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Appearance Solid
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Molecular Weight 441.27
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Formula C18H18Cl2N4O5
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Color White to off-white
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SMILES
O=C(CC1=CC(OC)=C(C=C1[N+]([O-])=O)OC)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (113.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2662 mL | 11.3309 mL | 22.6619 mL | 56.6547 mL |
| 5 mM | 0.4532 mL | 2.2662 mL | 4.5324 mL | 11.3309 mL | |
| 10 mM | 0.2266 mL | 1.1331 mL | 2.2662 mL | 5.6655 mL | |
| 15 mM | 0.1511 mL | 0.7554 mL | 1.5108 mL | 3.7770 mL | |
| 20 mM | 0.1133 mL | 0.5665 mL | 1.1331 mL | 2.8327 mL | |
| 25 mM | 0.0906 mL | 0.4532 mL | 0.9065 mL | 2.2662 mL | |
| 30 mM | 0.0755 mL | 0.3777 mL | 0.7554 mL | 1.8885 mL | |
| 40 mM | 0.0567 mL | 0.2833 mL | 0.5665 mL | 1.4164 mL | |
| 50 mM | 0.0453 mL | 0.2266 mL | 0.4532 mL | 1.1331 mL | |
| 60 mM | 0.0378 mL | 0.1888 mL | 0.3777 mL | 0.9442 mL | |
| 80 mM | 0.0283 mL | 0.1416 mL | 0.2833 mL | 0.7082 mL | |
| 100 mM | 0.0227 mL | 0.1133 mL | 0.2266 mL | 0.5665 mL |