2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Cathepsin X-IN-1

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 µM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic.

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Cathepsin X-IN-1

Cathepsin X-IN-1 화학구조

CAS No. : 2418577-51-0

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Cathepsin X-IN-1 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Cathepsin X-IN-1

View All Cathepsin Isoform Specific Products:

View All Isoforms
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 µM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic[1].

IC50 & Target

IC50: 7.13 µM (Cathepsin X)[1]
분자량

315.35

화학식

C15H13N3O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#CCN1C=CN=C1SCC(C2=CC3=C(OCCO3)C=C2)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도
In Vitro: 

DMSO : ≥ 100 mg/mL (317.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 4.85 mg/mL (15.38 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1711 mL 15.8554 mL 31.7108 mL
5 mM 0.6342 mL 3.1711 mL 6.3422 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.1711 mL 15.8554 mL 31.7108 mL 79.2770 mL
5 mM 0.6342 mL 3.1711 mL 6.3422 mL 15.8554 mL
10 mM 0.3171 mL 1.5855 mL 3.1711 mL 7.9277 mL
15 mM 0.2114 mL 1.0570 mL 2.1141 mL 5.2851 mL
DMSO 20 mM 0.1586 mL 0.7928 mL 1.5855 mL 3.9638 mL
25 mM 0.1268 mL 0.6342 mL 1.2684 mL 3.1711 mL
30 mM 0.1057 mL 0.5285 mL 1.0570 mL 2.6426 mL
40 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9819 mL
50 mM 0.0634 mL 0.3171 mL 0.6342 mL 1.5855 mL
60 mM 0.0529 mL 0.2643 mL 0.5285 mL 1.3213 mL
80 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9910 mL
100 mM 0.0317 mL 0.1586 mL 0.3171 mL 0.7928 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cathepsin X-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cathepsin X-IN-12418577-51-0CathepsinPC-3 cellsmigrationneurodegenerative diseaseslow cytotoxicInhibitorinhibitorinhibit

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상품명:
Cathepsin X-IN-1
Cat. No.:
HY-146985
수량:
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