ccβ acetate
Based on 1 Customer Validation
ccβ acetate is a 17-residue peptide that folds into a coiled-coil trimer at low temperatures and aggregates to form amyloid fibrils at high temperatures. ccβ acetate serves as a simple model system for investigating α-helix to β-sheet conformational transitions and template-mediated aggregation processes associated with prion and amyloidogenic diseases. ccβ acetate can be used in studies of prion diseases and Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C88H157N29O27·xC2H4O2
- Molecular Weight:2053.37 (free base)
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
ccβ acetate forms a thermodynamically stable native-like coiled-coil α-helical structure at temperatures below 0.71 ε/KB, and transitions to a β-strand-rich structure at temperatures above 0.71 ε/KB[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 2053.37 (free base)
-
Formula C88H157N29O27·xC2H4O2
-
SMILES
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N.CC(O)=O.[x]
-
Sequence
Ser-Ile-Arg-Glu-Leu-Glu-Ala-Arg-Ile-Arg-Glu-Leu-Glu-Leu-Arg-Ile-Gly
-
Sequence Shortening
SIRELEARIRELELRIG
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 33.33 mg/mL (Need ultrasonic)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ccβ acetate Related Classifications
HY-P10534A Related Classifications
Powered by Bioz