Cefepime-d3 sulfate
Based on 1 Customer Validation
Cefepime-d3 sulfate (BMY-28142-d3 sulfate) is the deuterated-labeled Cefepime-d8 sulfate (HY-143831S). Cefepime-d8 sulfate (BMY-28142-d8 sulfate) is the deuterated-labeled Cefepime sulfate (HY-B0616). Cefepime (BMY-28142) sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC50 of 21.115 mM and a Ki of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABAA receptors. Cefepime sulfate exhibits high affinity for PBPs, inhibits the growth of both Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamases.
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- Pureté : 99.20%
- CAS No.: 131857-28-8
- Formule: C19H23D3N6O9S3
- Masse moléculaire:581.66
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 131857-28-8
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Unlabeled CAS 107648-78-2
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Appearance Solid
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Masse moléculaire 581.66
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Formule C19H23D3N6O9S3
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Color Off-white to light brown
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SMILES
O=S(O)([O-])=O.O=C1[C@H]([C@]2(SCC(C[N+]3(CCCC3)C([2H])([2H])[2H])=C(N21)C(O)=O)[H])NC(/C(C4=CSC(N)=N4)=N\OC)=O
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Synonyms
BMY-28142-d3 sulfate
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (283 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cefepime-d3 sulfate Related Classifications
HY-W654100 Related Classifications
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Keywords
- Cefepime-d3
- 131857-28-8
- BMY-28142-d3
- Isotope-Labeled Compounds
- Antibiotic
- Bacterial
- GABA Receptor
- Penicillin-binding protein (PBP)
- Gamma-aminobutyric acid Receptor
- γ-Aminobutyric acid Receptor
- nosocomial infections
- blood-brain barrier
- gram-negative bacteria
- pneumonia
- gram-positive bacteria
- complicated urinary tract infections
- GABA_A receptors
- anaerobic Bacteroides species
- TEM plasmid β-lactamase
- hPON1
- Inhibitor
- inhibitor
- inhibit