Ceftazidime EP Impurity E
Ceftazidime EP Impurity E is an impurity of Ceftazidime (HY-B0953). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.
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- CAS No.: 102772-66-7
- 화학식: C22H22N6O7S2
- 분자량:546.58
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
All Beta-lactamase Isoforms
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Biological Activity
제품 설명
In Vitro
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Cell Line:P. aeruginosa strains (PAO1, PA1, PA2)
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Concentration:0-8 µg/mL approximately
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Incubation Time:24 h
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Result:Displayed antibacterial and anti-biofilm activities with MIC values of 2-4 µg/mL.
In Vivo
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Animal Model:Murine thigh infection model[4]
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Dosage:2000 mg
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Administration:2 h infusion of injection, every 8 h for 24 h.
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Result:Reduced bacterial density against the isogenic NDM (New Delhi metallo-β-lactamase) strain.
Chemical Information
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CAS No. 102772-66-7
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분자량 546.58
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화학식 C22H22N6O7S2
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SMILES
O=C([O-])C(N1[C@@]([H])([C@@H](C1=O)NC(C(C2=CSC(N)=N2)=NOC(C)(C(O)=O)C)=O)SC3)=C3C[N+]4=CC=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceftazidime EP Impurity E Related Classifications
HY-Z3473 Related Classifications
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