Cereulide-13C6
Based on 1 Customer Validation
Cereulide-13C6 is a deuterated form of Cereulide. Cereulide is an orally active, blood-brain barrier-permeable emetic toxin. Cereulide acts as a potassium ionophore that inserts into membranes, forms complexes with K+, and transports K+ from the cytoplasm into the mitochondrial matrix. Cereulide disrupts the electrochemical gradient of the inner mitochondrial membrane, leading to mitochondrial swelling and dysfunction, uncoupling of oxidative phosphorylation, inhibition of ATP synthesis, ROS accumulation, and ultimately triggering apoptosis and autophagy. Cereulide exhibits multi-organ toxicity and can be used for research on emetic food poisoning.
For research use only. We do not sell to patients.
- Purity: 97%
- CAS No.: 1487375-69-8
- Formula: C5113C6H96N6O18
- Molecular Weight:1159.36
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1487375-69-8
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Unlabeled Cas 157232-64-9
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Appearance Liquid
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Molecular Weight 1159.36
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Formula C5113C6H96N6O18
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Color Colorless to light yellow
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SMILES
CC(C)C[C@H]1O[13C]([C@@H](NC([C@@H](OC([C@H](NC([C@H](O[13C]([C@@H](NC([C@@H](OC([C@H](NC([C@H](O[13C]([C@@H](NC([C@@H](OC([C@H](NC1=O)[13CH3])=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)[13CH3])=O)C(C)C)=O)C(C)C)=O)CC(C)C)=O)[13CH3])=O)C(C)C)=O)C(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (276 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cereulide-13C6 Related Classifications
HY-P3003S Related Classifications
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