ACT-373898
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist.
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- CAS. Nr.: 1433875-14-9
- Formel: C15H17BrN4O5S
- Molecular Weight:445.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
The elimination half-life (t1/2) is approximately 16 h for Macitentan, and ACT-373898 has a similar pharmacokinetic (PK) profile to Macitentan[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1433875-14-9
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Molecular Weight 445.29
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Formel C15H17BrN4O5S
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SMILES
O=C(O)COC1=NC=NC(NS(=O)(NCCC)=O)=C1C2=CC=C(Br)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)