AEG40826
AEG40826 (HGS1029), a second mitochondria-derived activator of caspases (SMAC) mimetic, is an inhibitor of apoptosis (IAP) inhibitor. AEG40826 degrades cellular IAP1 (cIAP1) and blocks TNF-α pro-survival signaling. AEG40826 can be used for cancer research.
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- CAS. Nr.: 949963-04-6
- Formel: C58H80N10O8
- Molecular Weight:1045.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 949963-04-6
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Molecular Weight 1045.32
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Formel C58H80N10O8
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SMILES
CN[C@@H](C)C(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@@H](C1)NC(C2=CC=C(C=C2)C(N[C@@H]3CN([C@@H](C3)C(N[C@H]4C5=CC=CC=C5CCC4)=O)C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)=O)=O)C(N[C@H]6C7=CC=CC=C7CCC6)=O)=O)=O
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Synonyms
HGS1029
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AEG40826 Related Classifications
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