AMXI-5001
Based on 1 Customer Validation
AMXI-5001 is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor. MXI-5001 exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors. AMXI-5001 induces complete regression of established tumors, including exceedingly large tumors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.25%
- CAS. Nr.: 2170491-77-5
- Formel: C25H20FN5O3
- Molecular Weight:457.46
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2170491-77-5
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Appearance Solid
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Molecular Weight 457.46
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Formel C25H20FN5O3
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Color Off-white to light yellow
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SMILES
O=C(NC1=NC2=C(N1)C=C(C3=C(F)C=CC(CC4=NNC(C5=C4C=CC=C5)=O)=C3)C=C2)OCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (109.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1860 mL | 10.9299 mL | 21.8598 mL | 54.6496 mL |
| 5 mM | 0.4372 mL | 2.1860 mL | 4.3720 mL | 10.9299 mL | |
| 10 mM | 0.2186 mL | 1.0930 mL | 2.1860 mL | 5.4650 mL | |
| 15 mM | 0.1457 mL | 0.7287 mL | 1.4573 mL | 3.6433 mL | |
| 20 mM | 0.1093 mL | 0.5465 mL | 1.0930 mL | 2.7325 mL | |
| 25 mM | 0.0874 mL | 0.4372 mL | 0.8744 mL | 2.1860 mL | |
| 30 mM | 0.0729 mL | 0.3643 mL | 0.7287 mL | 1.8217 mL | |
| 40 mM | 0.0546 mL | 0.2732 mL | 0.5465 mL | 1.3662 mL | |
| 50 mM | 0.0437 mL | 0.2186 mL | 0.4372 mL | 1.0930 mL | |
| 60 mM | 0.0364 mL | 0.1822 mL | 0.3643 mL | 0.9108 mL | |
| 80 mM | 0.0273 mL | 0.1366 mL | 0.2732 mL | 0.6831 mL | |
| 100 mM | 0.0219 mL | 0.1093 mL | 0.2186 mL | 0.5465 mL |
AMXI-5001 Related Classifications
HY-145734 Related Classifications
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