PROTAC STING Degrader-1 control
Based on 1 publication(s) in Google Scholar
PROTAC STING Degrader-1 control serves as the negative control for PROTAC STING Degrader-1 (HY-150608). PROTAC STING Degrader-1 is a PROTAC degrader targeting the STING pathway.
(Pink: STING ligand (HY-138682); Blue: Cereblon ligand (HY-W460193); Black: linker (HY-W008296)).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.04%
- CAS. Nr.: 2767427-87-0
- Formel: C35H35N7O10
- Molecular Weight:713.69
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PROTAC STING Degrader-1 control
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Biologische Aktivität
Beschreibung
In Vitro
Chemical Information
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CAS. Nr. 2767427-87-0
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Appearance Solid
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Molecular Weight 713.69
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Formel C35H35N7O10
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Color Light yellow to yellow
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SMILES
[O-][N+](C1=CC=C(C(NC2=CC=C(NC(/C=C/C(NCCCCCCNC3=C4C(C(N(C4=O)C5CCC(N(C5=O)C)=O)=O)=CC=C3)=O)=O)C=C2)=O)O1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Free Radic Biol Med
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation. [Abstract]2025 Dec 18:244:422-434. PMID: 41421415
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (140.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.4012 mL | 7.0058 mL | 14.0117 mL | 35.0292 mL |
| 5 mM | 0.2802 mL | 1.4012 mL | 2.8023 mL | 7.0058 mL | |
| 10 mM | 0.1401 mL | 0.7006 mL | 1.4012 mL | 3.5029 mL | |
| 15 mM | 0.0934 mL | 0.4671 mL | 0.9341 mL | 2.3353 mL | |
| 20 mM | 0.0701 mL | 0.3503 mL | 0.7006 mL | 1.7515 mL | |
| 25 mM | 0.0560 mL | 0.2802 mL | 0.5605 mL | 1.4012 mL | |
| 30 mM | 0.0467 mL | 0.2335 mL | 0.4671 mL | 1.1676 mL | |
| 40 mM | 0.0350 mL | 0.1751 mL | 0.3503 mL | 0.8757 mL | |
| 50 mM | 0.0280 mL | 0.1401 mL | 0.2802 mL | 0.7006 mL | |
| 60 mM | 0.0234 mL | 0.1168 mL | 0.2335 mL | 0.5838 mL | |
| 80 mM | 0.0175 mL | 0.0876 mL | 0.1751 mL | 0.4379 mL | |
| 100 mM | 0.0140 mL | 0.0701 mL | 0.1401 mL | 0.3503 mL |
PROTAC STING Degrader-1 control Related Classifications
HY-157570 Related Classifications
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