N-Me-Thalidomide 4-fluoride
Based on 1 Customer Validation
N-Me-Thalidomide 4-fluoride is a ligand for E3 ligase, used for the synthesis of Anti-inflammatory agent 70 (HY-157570).
For research use only. We do not sell to patients.
- Purity: 99.41%
- CAS No.: 2244520-92-9
- Formula: C14H11FN2O4
- Molecular Weight:290.25
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2244520-92-9
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Appearance Solid
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Molecular Weight 290.25
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Formula C14H11FN2O4
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Color Off-white to gray
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SMILES
O=C1C2=C(C(N1C3C(N(C)C(CC3)=O)=O)=O)C(F)=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 16.67 mg/mL (57.43 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4453 mL | 17.2265 mL | 34.4531 mL | 86.1326 mL |
| 5 mM | 0.6891 mL | 3.4453 mL | 6.8906 mL | 17.2265 mL | |
| 10 mM | 0.3445 mL | 1.7227 mL | 3.4453 mL | 8.6133 mL | |
| 15 mM | 0.2297 mL | 1.1484 mL | 2.2969 mL | 5.7422 mL | |
| 20 mM | 0.1723 mL | 0.8613 mL | 1.7227 mL | 4.3066 mL | |
| 25 mM | 0.1378 mL | 0.6891 mL | 1.3781 mL | 3.4453 mL | |
| 30 mM | 0.1148 mL | 0.5742 mL | 1.1484 mL | 2.8711 mL | |
| 40 mM | 0.0861 mL | 0.4307 mL | 0.8613 mL | 2.1533 mL | |
| 50 mM | 0.0689 mL | 0.3445 mL | 0.6891 mL | 1.7227 mL |