AR-C67085
AR-C67085 (PSB 0413; FPL 67085) is a potent platelet P2T receptor antagonist with an pIC50 value of 8.60. AR-C67085 inhibits ADP-induced platelet aggregation.
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- CAS. Nr.: 164992-25-0
- Formel: C14H22Cl2N5O12P3S
- Molecular Weight:648.24
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
P2T[1]
Chemical Information
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CAS. Nr. 164992-25-0
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Molecular Weight 648.24
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Formel C14H22Cl2N5O12P3S
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SMILES
NC1=NC(SCCC)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(C(Cl)(Cl)P(O)(O)=O)(O)=O)(O)=O)O3
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Synonyms
AR-C67085MX; PSB 0413; FPL 67085
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Humphries RG, et al. A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis. Trends Pharmacol Sci. 1995 Jun;16(6):179-81. [Content Brief]
[2]. Ingall AH, et al. Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy. J Med Chem. 1999 Jan 28;42(2):213-20. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)